Joseph V Bonventre Selected Research

Phospholipases A2 (Phospholipase A2)

1/2016	The Prostaglandin E2-EP3 Receptor Axis Regulates Anaplasma phagocytophilum-Mediated NLRC4 Inflammasome Activation.
11/2015	Group IVA Cytosolic Phospholipase A2 Regulates the G2-to-M Transition by Modulating the Activity of Tumor Suppressor SIRT2.
5/2014	Cytosolic phospholipase A2 protein as a novel therapeutic target for spinal cord injury.
1/2013	Cytosolic phospholipase A(2)α and eicosanoids regulate expression of genes in macrophages involved in host defense and inflammation.
11/2008	Phospholipase A2 reduction ameliorates cognitive deficits in a mouse model of Alzheimer's disease.
10/2007	Deletion of secretory group V phospholipase A2 attenuates cell migration and airway hyperresponsiveness in immunosensitized mice.
4/2005	Cytoplasmic phospholipase A2 deletion enhances colon tumorigenesis.
8/2004	Decreased lung tumorigenesis in mice genetically deficient in cytosolic phospholipase A2.
7/2003	Deletion of cytosolic phospholipase A2 promotes striated muscle growth.

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Joseph V Bonventre Research Topics

Disease

56	Acute Kidney Injury (Acute Renal Failure) 01/2022 - 01/2002
33	Inflammation (Inflammations) 07/2022 - 01/2002
27	Fibrosis (Cirrhosis) 07/2022 - 12/2002
23	Chronic Renal Insufficiency 01/2022 - 03/2009
22	Ischemia 10/2021 - 01/2002
13	Kidney Diseases (Kidney Disease) 01/2022 - 12/2004
12	Chronic Kidney Failure (Chronic Renal Failure) 07/2022 - 04/2010
12	Proteinuria 03/2021 - 06/2003
11	Neoplasms (Cancer) 03/2016 - 08/2004
10	Reperfusion Injury 10/2021 - 12/2004
8	Infections 11/2017 - 02/2008
7	Hypertension (High Blood Pressure) 01/2022 - 12/2012
6	Albuminuria 10/2018 - 02/2011
5	Diabetic Nephropathies (Diabetic Nephropathy) 01/2022 - 10/2002
5	Renal Insufficiency (Renal Failure) 01/2022 - 05/2005
5	Pneumonia (Pneumonitis) 12/2020 - 01/2004
5	Ureteral Obstruction 11/2019 - 01/2002
5	Hypoxia (Hypoxemia) 12/2018 - 06/2002
5	Carcinogenesis 03/2016 - 07/2003
4	COVID-19 01/2022 - 12/2020
4	Heart Failure 11/2019 - 05/2017
4	Renal Cell Carcinoma (Grawitz Tumor) 02/2014 - 04/2005
3	Atherosclerosis 07/2022 - 12/2012
3	Type 2 Diabetes Mellitus (MODY) 01/2022 - 01/2020
3	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 10/2021 - 02/2011
3	Mitochondrial Diseases (Mitochondrial Disease) 01/2020 - 01/2016
3	Necrosis 09/2017 - 01/2008
3	Autosomal Dominant Polycystic Kidney (ADPKD) 10/2016 - 10/2013
3	Sepsis (Septicemia) 01/2013 - 03/2007
2	Disease Progression 07/2022 - 01/2017
2	Stroke (Strokes) 07/2022 - 01/2011
2	Anemia 11/2021 - 01/2021
2	Nephrotic Syndrome (Syndrome, Nephrotic) 07/2018 - 01/2016
2	Hypotension (Low Blood Pressure) 01/2016 - 06/2003

Drug/Important Bio-Agent (IBA)

54	Biomarkers (Surrogate Marker)IBA 07/2022 - 01/2004
31	CreatinineIBA 01/2022 - 11/2005
20	Proteins (Proteins, Gene)FDA Link 07/2022 - 12/2002
12	Phospholipases (Phospholipase)IBA 11/2021 - 04/2005
10	EicosanoidsIBA 01/2018 - 04/2005
9	Cisplatin (Platino)FDA LinkGeneric 11/2019 - 05/2005
9	Phospholipases A2 (Phospholipase A2)IBA 01/2016 - 07/2003
8	AlbuminsIBA 01/2021 - 09/2010
8	Arachidonic Acid (Vitamin F)IBA 11/2017 - 07/2003
7	Phosphotransferases (Kinase)IBA 01/2022 - 01/2002
7	Pharmaceutical PreparationsIBA 01/2021 - 01/2009
6	CytokinesIBA 01/2022 - 10/2006
6	Angiotensin IIIBA 11/2021 - 04/2015
6	Hexosaminidases (Hexosaminidase)IBA 01/2017 - 02/2006
6	Lipocalin-2IBA 01/2017 - 02/2008
5	Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA 07/2022 - 01/2020
5	NitrogenIBA 11/2018 - 02/2006
5	CollagenIBA 03/2015 - 01/2004
4	Glucose (Dextrose)FDA LinkGeneric 07/2022 - 10/2003
4	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 07/2022 - 11/2015
4	MucinsIBA 01/2022 - 10/2006
4	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 05/2011
4	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2018 - 01/2007
4	Peptides (Polypeptides)IBA 01/2017 - 10/2002
4	LigandsIBA 11/2013 - 12/2006
4	Urea (Carbamide)FDA LinkGeneric 01/2013 - 02/2006
4	ProstaglandinsIBA 01/2013 - 01/2004
3	Urokinase Plasminogen Activator ReceptorsIBA 07/2022 - 03/2021
3	aristolochic acid I (aristolochic acid)IBA 01/2022 - 01/2013
3	Glutens (Glutelin)IBA 01/2021 - 07/2018
3	Oxygen (Dioxygen)IBA 12/2020 - 06/2002
3	Biological ProductsIBA 10/2018 - 08/2012
3	Phospholipids (Phosphatides)FDA LinkGeneric 11/2017 - 04/2015
3	8- hydroxy- 11,12- epoxyeicosa- 5,9,14- trienoic acidIBA 11/2017 - 08/2017
3	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 03/2016 - 01/2002
3	Cystatin CIBA 04/2015 - 09/2009
2	SodiumIBA 07/2022 - 01/2009
2	Epidermal Growth Factor (EGF)IBA 07/2022 - 10/2021
2	Immunoglobulins (Immunoglobulin)IBA 01/2022 - 05/2011
2	Type II Tumor Necrosis Factor ReceptorsIBA 01/2022 - 01/2022
2	Focal Adhesion Protein-Tyrosine KinasesIBA 01/2022 - 12/2011
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2022 - 01/2013
2	Type I Tumor Necrosis Factor ReceptorsIBA 01/2022 - 01/2022
2	Dipeptidyl-Peptidase IV InhibitorsIBA 01/2022 - 12/2020
2	Interleukin-22 (IL-22)IBA 11/2021 - 01/2021
2	Fatty Acids (Saturated Fatty Acids)IBA 01/2021 - 11/2008
2	Transforming Growth Factor beta (TGF-beta)IBA 09/2019 - 01/2007
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 11/2018 - 12/2004
2	phosphatidylserine receptorIBA 10/2018 - 09/2013
2	Small Interfering RNA (siRNA)IBA 01/2018 - 10/2002
2	Protein Isoforms (Isoforms)IBA 11/2017 - 05/2014
2	Chemotactic FactorsIBA 11/2017 - 10/2017
2	LipidsIBA 10/2017 - 08/2004
2	Fatty Acid-Binding ProteinsIBA 01/2017 - 04/2010
2	Group IV Phospholipases A2IBA 03/2016 - 04/2010
2	EnzymesIBA 03/2016 - 08/2004
2	Prostaglandin-E SynthasesIBA 01/2016 - 08/2004
2	Adenosine Triphosphate (ATP)IBA 01/2016 - 10/2003
2	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 01/2016 - 06/2005
2	Dinoprostone (PGE2)FDA Link 01/2016 - 08/2004
2	Gentamicins (Gentamicin)FDA LinkGeneric 10/2014 - 07/2009

Therapy/Procedure

19	Therapeutics 01/2022 - 12/2004
3	Renal Dialysis (Hemodialysis) 01/2022 - 01/2002
3	Nephrectomy 01/2017 - 04/2005
2	Renal Replacement Therapy (Therapies, Renal Replacement) 01/2022 - 11/2017
2	Cardiopulmonary Bypass (Heart-Lung Bypass) 11/2018 - 09/2009